Salter Harris Fractures

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Salter Harris Fractures
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Common Bony Conditions

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Background: Salter-Harris fractures are fractures through a growth plate; therefore, they are unique to pediatric patients. Several types of fractures have been categorized by the involvement of the physis, metaphysis, and epiphysis. The classification of the injury is important because it affect the treatment of the patient and provides clues to possible long-term complications.

Pathophysiology: The histologic features of the physis are important for understanding the prognosis of physeal fractures. The germinal layer of the cartilage is on the epiphysis and derives nutrition from the epiphyseal vessels. Cartilage cells grow from the epiphysis towards the metaphysis, forming columns of cells that degenerate, fragment, and undergo hypertrophy. The fragments of cells mineralize. This is the zone of provisional calcification forming the metaphyseal border, and is not bone. Note that no circulation exists in the cartilage zone.

Neovascularization occurs from the metaphysis towards the epiphysis. Endothelial cells transform into osteoblasts and use the degenerate cell debris to form primary immature bone. This immature bone progressively is remodeled to mature woven bone and further is remodeled by cutting cones to form mature haversian system bone. Damage to either epiphyseal or metaphyseal vascular supply disrupts bone growth; however, damage to the layer of cartilage may not be significant if the surfaces are reapposed, and vascular supply to the growing cartilage is not permanently interrupted. When the 2 vascular beds touch, the physis is closed (fused) and no further bone growth is possible.

Age: Salter-Harris fractures are injuries through the physis. Therefore, by definition, they must occur before the physis closes. Typically, physis closure occurs during the teenage years.

Clinical Details: The classification of Salter-Harris fractures is used to describe the extent and site of the epiphyseal injuries. The basic types of injuries include the following:

 
bulletType I
bulletA type 1 fracture is transverse fracture through the hypertrophic zone of the physis. In this injury, the width of the physis is increased. The growing zone of the physis usually is not injured, and growth disturbance is uncommon.
bulletOn clinical examination, the child has point tenderness at the epiphyseal plate, which is suggestive of a type I fracture.
bulletType II
bulletA type II fracture is a fracture through the physis and metaphysis, but the epiphysis is not involved in the injury.
bulletThese fractures may cause minimal shortening; however, the injuries rarely result in functional limitations.
bulletType II is the most common Salter-Harris fracture.
bulletType III
bulletA type III fracture is a fracture through the physis and the epiphysis. This fracture passes through the hypertrophic layer of the physis and extends to split the epiphysis, inevitably damaging the reproductive layer of the physis.
bulletThis type of fracture is prone to chronic disability because, by crossing the physis, it extends into the articular surface of the bone.
bulletHowever, type III fractures rarely result in significant deformity; therefore, they have a relatively favorable prognosis.
bulletA type of ankle fracture termed a Tillaux fracture is a type of Salter-Harris type III fracture that is prone to disability.
bulletThe treatment for this fracture often is surgical.

 

bulletType IV
bulletA Type IV fracture involves all 3 elements of the bone: The fracture passes through the epiphysis, physis, and metaphysis.
bulletSimilar to a type III fracture, a type IV fracture also is an intraarticular fracture; thus, it can result in chronic disability.
bulletBy interfering with the growing layer of cartilage cells, these fractures can cause premature focal fusion of the involved bone. Therefore, these injuries can cause deformity of the joint.

 

bulletType V
bulletA type V injury is a compression or crush injury of the epiphyseal plate with no associated epiphyseal or metaphyseal fracture.
bulletThis fracture is associated with growth disturbances at the physis. Initially, diagnosis may be difficult, and it often is made retrospectively after premature closure of the physis is observed. In the older teenagers, the diagnosis is particularly difficult.
bulletThe clinical history is paramount in the diagnosis of this fracture. A typical history is that of an axial load injury.
bulletThese injuries have a poor functional prognosis.

When all types of Salter-Harris fractures are considered, the rate of growth disturbance is approximately 30%. However, only 2% of Salter-Harris fractures result in a significant functional disturbance.

Rare types of Salter-Harris fractures include the following:
bulletType VI: This is a rare injury and consists of an injury to the perichondral structures.
bulletType VII: This is an isolated injury to the epiphyseal plate.
bulletType VIII: This is an isolated injury to the metaphysis, with a potential injury related to endochondral ossification.
bulletType IX: This is an injury to the periosteum that may interfere with membranous growth.

Preferred Examination: Radiography always is the preferred examination in a suspected fracture. The use of another modality should not be considered until appropriate plain film radiography has been performed.

In cases of severe injury in which the patient has acute pain, appropriate radiographic examination of the involved area may be difficult because of inadequate patient positioning. In these cases, CT may be beneficial in evaluating the injury after a radiologist has evaluated the plain radiographs. However, the cost of CT may prohibit its use in all cases in which the area of interest is suboptimally evaluated. CT should be considered only when radiographic findings are insufficient. Typically, an orthopedic surgeon and a radiologist make the decision to perform CT.

If an additional study is performed, its purpose is to determine the appropriate management and assist in surgical planning. Thus, the surgeon performing the operation is best suited to request the imaging study. When further definition of fractures may help in making management decisions or when the injury does not responding to conservative management, the radiologist or orthopedic surgeon can recommend an appropriate examination to perform after plain radiography.

Currently, 2 radiologic examinations can be performed to further evaluate fractures: (1) CT with multiplanar reconstruction and (2) MRI. MRI depicts marrow edema, whereas CT shows cross-sectional bone detail and tomographic multiplanar information. The use of MRI in the evaluation of fractures is described below, but it is still in its infancy. At the present time, MRI is not the standard of care. CT is used more commonly; typically, it is used for planning surgery.

Limitations of Techniques: The primary disadvantages of MRI are related to its expense, time requirement, and availability, which limit the routine use of MRI. As techniques and software improve, the use of MRI in the acute trauma setting is likely to increase.
  DIFFERENTIALS Section 3 of 10   Click here to go to the previous section in this topic Click here to go to the top of this page Click here to go to the next section in this topic
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Ankle, Fractures
Elbow Trauma - Pediatric
Wrist, Scaphoid Fractures and Complications

  X-RAY Section 4 of 10   Click here to go to the previous section in this topic Click here to go to the top of this page Click here to go to the next section in this topic
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Findings: X-ray findings vary according to the type of Salter-Harris fracture.

With type I fractures, initial radiographs may suggest separation of the physis, but this separation may not be apparent. However, soft tissue swelling is present, and its center typically overlies the physis (see Image 2). Follow-up radiographs obtained 7-10 days after injury help in establishing the diagnosis. New bone growth (ie, adjacent sclerosis and periosteal reaction) along the epiphyseal plate confirms the diagnosis of a Salter-Harris type I fracture.

In type II fractures, the fracture line passes through the metaphysis into the epiphyseal plate, but no fracture is observed in the epiphysis (see Image 3). The metaphyseal fragment is sometimes called the Thurston-Holland fragment.

Type III fractures pass through the hypertrophic layer of the physis and extend to split the epiphysis (see Image 4). The fracture crosses the physis and extends into the articular surface of the bone.

Type IV fractures pass through the epiphysis, physis, and metaphysis (see Image 5). Similar to a type III fracture, a type IV fracture also is an intraarticular fracture.

In type V injuries, initial plain radiographs may not show a fracture line, similar to images of type I fractures (see Image 6). However, soft tissue swelling at the physis is present. A compression or crush injury of the epiphyseal plate is present without associated epiphyseal or metaphyseal fracture

 

CAT SCAN

Section 5 of 10   

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Findings: CT has an important role in the evaluation of epiphyseal injuries. Rogers and Poznanski discussed the role of CT with the use of a bone algorithm and multiplanar reconstruction of multiplanar initial images. With CT, a considerable amount of information regarding the nature of the fracture can be gathers. CT techniques typically are used in patients prior to surgery, after a fracture is diagnosed on the basis of plain radiographic findings.

Multiplanar CT findings are similar to plain radiographic findings.

Degree of Confidence: The computer program is able to compensate for imprecise patient positioning. True lateral and true anteroposterior (AP) views of the bone in question can be obtained. As with any study, physicians who request these costly studies should have the knowledge and experience needed to interpret the images. Orthopedic surgeons may be the ones to request CT examinations; however, any physician can order them in consultation with a radiologist.

The advantage of CT compared with MRI is its availability and the speed with which images can be obtained. The disadvantage is that CT requires a relatively large dose of radiation for diagnostic imaging. Raw-data images typically are obtained with 1-mm sections and a high milliampere technique; however, the high collimation reduces the total amount of exposure.

In the near future, multi–detector row technology is likely to affect the utility of CT in the detailed evaluation of fractures.

 

MRI

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Findings: On MRIs, the typical findings of Salter-Harris fractures include a signal void on T1-weighted images. On T2-weighted images, increased signal intensity, which is consistent with edema, is depicted around the fracture site.

MRI is used for surgical planning. Craig et al discussed the use of MRI in evaluating partial closure of the growth plates. Patients with functional or growth abnormalities were examined with MRI, and the exact nature of the defects were well described. These findings helped orthopedic surgeons to plan appropriate surgery.

Currently, no imaging technique is recommended and uniformly accepted for use in the evaluation of a Salter-Harris injury in children. However, from data in this section, one could conclude that MRI with multiple sequences provides more information than MRI with a single sequence. Thus, T1-weighted, T2-weighted, and gradient-echo imaging without contrast enhancement can be used to evaluate the bony structures, soft tissue, and physis well.

In a recent article, Craig et al suggested that a sagittal 3-dimensional (3D) spoiled gradient-recalled (SPGR) sequence is the best sequence for the evaluation of the physeal plate. (According to the article, this sequence is widely available.) Craig et al examined 22 patients with this sequence and claimed that this sequence provided excellent detail of the physeal plate. In addition to the SPGR sequence, they used 2-dimensional (2D) sagittal and coronal fast spin-echo sequences with an echo train length of 3 and 3-mm-thick sections with a 1-mm gap. The field of view was 14 cm. They also used 2D axial and coronal fast spin-echo imaging with fat saturation, an echo train length of 8, and 5-mm-thick sections with a 1.5-cm gap. The field of view was 18 cm.

If findings from the cited articles are compared, the use of a single sequence does significantly decrease the imaging time; in children examination time is an important factor. However, Craig et al strongly argues that SPGR provides the best images of the physis. To the author’s knowledge, no group has used SPGR alone in the examination of children with trauma. Again, the evaluation of Salter-Harris injuries in children is a new use of MRI technology, and no standard is uniformly accepted at this time.

Degree of Confidence: MRI is a relatively new technique. MRI is limited in the assessment of acutely injuries because of the length of time involved in the examination. Another limitation is the relative isolation of the patient within the machine.

Currently, MRI has limited utility in the evaluation of Salter-Harris fractures. Therefore, it is most efficiently applied by specialists with specific treatment questions. Orthopedic surgeons are the most appropriate physicians to request MRI; however, in consultation, a radiologist and a clinician may determine a specific need for MRI findings in a given case. Consultation with an orthopedic surgeon is likely to be helpful in complicated injuries that require treatment.

MRI in the setting of acute trauma has been discussed in 2 recent articles. Close and Strouse retrospectively evaluated 315 consecutive knee MRI in children with a history of trauma. They reported that MRI revealed several additional fractures that were not fully identified on plain radiographs, and, of the 8 fractures found with MRI, 7 had findings that changed the clinical management. This study was limited because of its retrospective nature and selection bias; however, the authors indicate that MRI is better than plain radiography in delineating the exact nature of an injury. In complex cases, this advantage may be of clinical importance.

False Positives/Negatives: Carey et al reviewed the correlation of MRI results and plain radiographic findings in Salter-Harris fractures and found a trend similar to that of Close and Strouse. In 2001, a Finnish study revealed no misclassification in patients with minor ankle fractures; MRI was helpful in evaluating complex injuries in the ankle.

A study performed in 1996 by Petite et al revealed a small benefit with the use of MRI versus plain radiography They found a misclassification rate of only 3% in patients with acute trauma. This study was limited because only gradient-echo imaging was used. Carey et al and Close and Strouse used multiple MRI techniques. The conclusion of Petite et al is similar to that of the other studies: MRI can be helpful in complex cases or when plain radiographic findings are normal and the clinical findings are highly suggestive of fracture.

 

ULTRASOUND

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Findings: Ultrasonography (US) has a limited role in the diagnosis of fractures.

Degree of Confidence: In a recent study, Hubner et al compared the results of primary US diagnosis of fractures with the results of plain radiography. They were able to accurately diagnose fractures with US; however, complex fractures were more difficult to assess with US. Salter-Harris type I fractures and nondisplaced fractures with less than 1 mm of separation were reliably detected with US.

 

NUCLEAR MEDICINE

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Findings: Although nuclear medicine studies had a role in the diagnosis of Salter-Harris fractures in the past, MRI and CT have replaced nuclear medicine study in the evaluation of subtle fractures.

 

PICTURES

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Caption: Picture 1. Illustration of uninjured bone

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Caption: Picture 2. Salter-Harris fracture type I

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Caption: Picture 3. Salter-Harris fracture type II

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Caption: Picture 4. Salter-Harris fracture type III

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Caption: Picture 5. Salter-Harris fracture type IV

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Caption: Picture 6. Salter-Harris fracture type V

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Caption: Picture 7. Salter-Harris type II fracture of the distal tibia

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Caption: Picture 8. Salter-Harris type III fracture of the distal tibia

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Caption: Picture 9. Salter-Harris type IV fracture of the distal tibia

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Caption: Picture 10. Anteroposterior (AP) plain radiograph of the knee in a child with persistent knee pain after trauma. The radiographic findings appear normal.

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Caption: Picture 11. Lateral view obtained in the same patient as in Image 10 shows only a joint effusion.

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Caption: Picture 12. Coronal MRI obtained several weeks after an initial radiograph was obtained to assess ligamentous injury shows an unexpected finding of a Salter-Harris type III fracture.

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Caption: Picture 13. Sagittal MRI in the same patient as in Image 10

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BIBLIOGRAPHY

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Brown JH, DeLuca SA: Growth plate injuries: Salter-Harris classification. Am Fam Physician 1992 Oct; 46(4): 1180-4[Medline].

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Carey J, Spence L, Blickman H, Eustace S: MRI of pediatric growth plate injury: correlation with plain film radiographs and clinical outcome. Skeletal Radiol 1998 May; 27(5): 250-5[Medline].

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Close BJ, Strouse PJ: MR of physeal fractures of the adolescent knee. Pediatr Radiol 2000 Nov; 30(11): 756-62[Medline].

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Craig JG, Cramer KE, Cody DD: Premature partial closure and other deformities of the growth plate: MR imaging and three-dimensional modeling. Radiology 1999 Mar; 210(3): 835-43[Medline].

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Hubner U, Schlicht W, Outzen S, et al: Ultrasound in the diagnosis of fractures in children. J Bone Joint Surg Br 2000 Nov; 82(8): 1170-3[Medline].

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Keret D, Mendez AA, Harcke HT, MacEwen GD: Type V physeal injury: a case report. J Pediatr Orthop 1990 Jul-Aug; 10(4): 545-8[Medline].

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Lohman M, Kivisaari A, Kallio P: Acute paediatric ankle trauma: MRI versus plain radiography. Skeletal Radiol 2001 Sep; 30(9): 504-11[Medline].

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Mac Nealy GA, Rogers LF, Hernandez R: Injuries of the distal tibial epiphysis: systematic radiographic evaluation. AJR Am J Roentgenol 1982 Apr; 138(4): 683-9[Medline].

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Petit P, Panuel M, Faure F: Acute fracture of the distal tibial physis: role of gradient-echo MR imaging versus plain film examination. AJR Am J Roentgenol 1996 May; 166(5): 1203-6[Medline].

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Rogers LF, Poznanski AK: Imaging of epiphyseal injuries. Radiology 1994 May; 191(2): 297-308[Medline].

 

                    
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                                Last modified: Wednesday December 24, 2003.